Evidence on Antimicrobial Efficacy of Commercial Toothpaste
M. Fazlina *
Department of Pharmacology, Faculty of Pharmacy, Asian Institute of Medical Sciences and Technology (AIMST) University, Kedah, Malaysia
A. Z. Nur
Department of Microbiology, Faculty of Medicine, Asian Institute of Medical Sciences and Technology (AIMST) University, Kedah, Malaysia
*Author to whom correspondence should be addressed.
Abstract
This study aims to determine the antimicrobial activity of different brand of commercially available toothpaste in Malaysian outlet, namely Colgate-Total, Mu’min, Tesco and Safi against selected oral microbiome. All the different toothpastes brand were tested for their antimicrobial activity against five oral pathogens namely Staphylococcus aureus, Proteus mirabilis, Salmonella typhi, Klebsiella pneumonia and Escherichia coli by using agar well diffusion method. Colgate-Total brand has the highest mean zone of inhibition (Z.O.I) on the test organisms (30.7 mm) followed by Safi brand (29.2 mm) and Tesco brand (12.5 mm) while Mu’min brand showed the least activity on the test micro-organisms (2.4 mm). The present work found Colgate-total brand toothpaste more effective in controlling pathogenic oral microflora as compared to other brand of toothpaste.
Keywords: Colgate-total, Mu’min, Tesco, Safi, antimicrobial, oral pathogens, zone of inhibition