In vitro Evaluation of Antibacterial and Antifungal Activities of Chrysophyllum albidum Stems Bark
Afees Adebayo Oladejo *
Department of Chemical Science, Biochemistry, Afe Babalola University, Ado Ekiti, Ekiti State, Nigeria.
Mashanty Obem Oyama
Department of Biological Science, Microbiology, Afe Babalola University, Ado Ekiti, Ekiti State, Nigeria.
Kehinde Olufeyisayo Ayeni
Department of Nutrition and Dietetics, Michael Okpara University of Agriculture, Umudike, Abia State, Nigeria.
Ebun-Olorun Ayo
Department of Biochemistry, Ekiti State University, Ado Ekiti, Ekiti State, Nigeria.
Adebowale Samuel Oyerinde
Department of Biochemistry, Ekiti State University, Ado Ekiti, Ekiti State, Nigeria.
*Author to whom correspondence should be addressed.
Abstract
The aim of this study was to evaluate the antibacterial and antifungi activities of ethanolic and methanolic extracts from Chrysophyllum albidum stem bark. The crude extracts were screened against Staphylococcus aureus, Escherichia coli, Klebsiella, Candida albicans and Aspergillus niger at different concentrations (3.125 mg/mL, 6.25 mg/mL, 12.5 mg/mL, 25 mg/mL, 50 mg/mL and 100 mg/mL) using the agar well diffusion technique. The ethanolic extracts had stronger inhibitory effects on test organisms than the methanolic extracts. The antimicrobial activity observed with the ethanolic extract ranged between 10 and 21.5 mm with no detectable activity on Aspergillus niger. Stronger antimicrobial activity was observed with the methanolic crude extracts at all concentrations with all test organisms. The result of this study is indicative that C. albidum stem bark extracts can be used in the treatment of infections.
Keywords: Chrysophyllum albidum, extracts, antimicrobial, antifungal.