Study of the Antibacterial Activity of Aqueous and Hydroethanolic Extracts of the Stem Bark of Erythroxylum emarginatum (Erythroxy laceae)
Kouakou Kouakou Victor *
Pharmacodynamics Biochemical Laboratory, UFR Biosciences, Felix Houphouet Boigny University, P.O.Box, 582, Abidjan 22- Côte d’Ivoire and National Laboratory of Public Health, P.O.Box, 1803 Abidjan 18 - Côte d’Ivoire
Fofie N'guessan Bra Yvette
National Laboratory of Public Health, P.O.Box, 1803 Abidjan 18 - Côte d’Ivoire and Laboratory of Pharmacognosy, UFR Pharmaceutical and Biological Sciences, Felix Houphouet Boigny University, P.O.Box, 582, Abidjan, Côte d’Ivoire.
Opkekon Aboua Thimotee
Organic Chemistry Laboratory and Natural Substances, UFR Sciences of Structures of Matter and Technology, Felix Houphouet Boigny University, P.O.Box, 582, Abidjan 22- Côte d’Ivoire
Yapi Houphouet Felix
Pharmacodynamics Biochemical Laboratory, UFR Biosciences, Felix Houphouet Boigny University, P.O.Box, 582, Abidjan 22- Côte d’Ivoire
Gbassi Komenan Gildas
National Laboratory of Public Health, P.O.Box, 1803 Abidjan 18 - Côte d’Ivoire and Analytical Chemistry Laboratory, UFR Pharmaceutical and Biological Sciences, Felix Houphouet Boigny University, P.O.Box, 582, Abidjan 22- Côte d’Ivoire
*Author to whom correspondence should be addressed.
Abstract
The aim of this work was to evaluate the in vitro antibacterial activity of of aqueous and hydoethanolic extracts of the stem bark of Erytroxylum emarginatum commonly used by the Ivorian population to treat various infections.
Bactericidal efficacy evaluated on strains such as Escherichia coli, Klebsilla pneumoniae, Pseudomonas aeruginosa, Staphylococcus aureus, and Streptococcus pneumonia.
The choice of selection of these bacterial strains due to high incidence as commonly aquired pnemonia in Africa and development of resistance. The methods used were the method of macrodilution in a liquid medium and the diffusion method in agar medium. Study results evinced minimum inhibitory concentration of aqueous and hydroethonolic extracts of Erytroxylum emarginatum on bactericidal action.
This screening study demonstarted the use of stem bark extracts of Erytroxylum emarginatum emphasise the alternate use for bacterial infections.
Keywords: Erythroxylum emarginatum, hydoethanolic extract, MIC, MBC, infections, antibacterial